You keep hearing here and there that Tenuate helps people lose weight no problem and wonder whether you should use it for your weight loss campaign.

Well, here’s your ultimate guide about Tenuate and Tenuate Dospan (Retard). But if you’re just here to get answers to most frequently asked questions, like Tenuate side effects, Tenuate dosing regimen and Where to buy Tenuate, do it right away.

If you’re still more into knowing everything about a medication that you plan on using and want to make sure that it’s exactly what you need, proceed with further reading and enjoy comprehensive information we have prepared for you.

What is Tenuate?

Tenuate is diet pills, which will help you curb excessive appetite and stop gluttony. By using this medicine, you will stop experiencing agonizing hunger, reduce the caloric content of your daily menu and begin to lose weight.

The main benefits of this medication are as follows:

  • It is an FDA-approved slimming product that really works.
  • It comes in two dosing strengths to accommodate for individual needs.
  • It may be prescribed to adolescents aged 16 years and over.

To fight overweight and obesity, you can use either Tenuate Dospan (75 mg extended-release (ER) Tablets) or Tenuate (25 mg immediate-release (IR) tablets).

Tenuate diet pills contain 25mg or 75mg of the active ingredient Diethylpropion. This ingredient is an anorectic, which suppresses appetite and thus reduces the irresistible cravings for food.

Different types of Tenuate tablets work identically, yet release Diethylpropion at different rates:

  • Due to the sustained release of the active ingredient, a single dose of Tenuate Dospan 75 mg helps control appetite throughout the day.
  • Thanks to the quick release of Diethylpropion, the anorexigenic effect achieved is fast, yet short-term, and lasts several hours.

Tenuate brand was first registered by William S. Merrell Company in February 1960. Tenuate history has been going on for more than half a century, and different pharmaceutical companies have been associated with this brand in different years.

Depending on the period of retail sales, the following companies were indicated as producers and suppliers of Tenuate:

  • Gruppo Lepetit
  • Marion merrell
  • Merrell Pharmaceuticals
  • Sanofi-aventis
  • Aventis Pharmaceuticals
  • Patheon Pharmaceuticals.

These days, Aventis Pharmaceuticals is specified as an exclusive supplier of the original Tenuate pills. This company owns a license to sell the original Tenuate tablets in the US.

In Europe, this drug is not available for sale, so obese Europeans order similar medications on online pharmacies. European consumers known Tenuate better under such brands, as:

  • Tenuate Retard (in Germany)
  • Tenuate Dospan (in the UK).

Who can use Tenuate?

Your doctor may recommend that you use Tenuate, if you comply with three conditions.

  1. Your BMI is equal to or greater than 30 (with or without risk factors)
  2. You can not lose weight with a balanced diet
  3. You can not “burn” excess calories with exercise.

The big mistake of many obese patients, though, is that they replace a balanced diet and physical exercises with Tenuate.

Any diet pills should be used as part of a weight loss program.

Regardless of whether the drug is used or not, during the treatment of obesity, patients must still introduce important lifestyle changes and make them permanent:

  • Reduce the calorie content of their daily menu.
  • Be physically active.

Make activity and diet an integral part of your life, and you will learn to control hunger without Tenuate or other anorectic drugs in just a few months.

Tenuate Dosage Guide

Your doctor tells you that you have to try to lose weight on your own without diet pills?

This is True!

But if unsuccessful attempts to get rid of unwanted fat are a mere disappointment, you can try to get a prescription for Tenuate.

After a medical examination and diagnostic tests, doctor can recommend you one of two possible dosing schedules for Tenuate.

Option 1 – 75 mg pill

  • Take a single dose of Tenuate 75mg every morning, preferably at the same time.
  • If you missed your daily dose of 75 mg , continue to use Tenuate exactly as prescribed by your Dr.
  • Do not increase your dose on the next day to make up for your missed dose of Tenuate.

Once-daily dose 75 mg helps you to:

  • Better manage your weight-loss program
  • Lose weight faster than with diet and exercise alone.

If a single dose of Tenuate 75mg does not work as long as you would like it to work, discuss with the doctor the possibility of changing the dosing schedule.

Do not change your dose unless your Dr. tells you to!

Option 2 – 25 mg pill

  1. Take a dose of 25mg in the morning
  2. Take a dose of 25 mg in the afternoon
  3. Take a dose of 25 mg in the evening.
  • The first two doses of Tenuate (25 mg + 25 mg ) will help you control your appetite throughout the day.
  • The evening dose of Tenuate 25 mg will help you successfully fight binging episodes.

Regardless of which Tenuate dosage you were prescribed, your results may vary, depending on your:

  • BMI
  • Diet
  • Activity.

Three steps on the way to a successful weight loss:

  • Use prescribed Tenuate doses,
  • Try to follow a low-fat diet,
  • Make efforts to increase physical activity.

… and as a reward, you will see how your weight begins to decrease.

Remember! You should regard the daily use of Tenuate not as “magic slimming pills”, but as an additional help in fighting extra calories.

Tenuate 25mg

Tenuate 25mg tablets are marketed exclusively to help people lose fat in different parts of the body. They are effective in fighting visceral and subcutaneous fat. This drug helps the patients whose overweight problems appeared several years ago or recently.

Tenuate tablets contain 25 mg of Diethylpropion as an active ingredient. After swallowing the tablet, Diethylpropion is quickly released, absorbed in the gastrointestinal tract, enters the bloodstream and further into the central nervous system.

  • Use of Tenuate 1 hour before food intake allows patients not to feel hungry and quickly saturate.
  • Use of Tenuate three times a day before the main meals allows to control appetite throughout the day.

White round Tenuate 25mg tablets are packed in bottles of 100 pieces. Each tablet engraved with “Tenuate 25” or “Merrell 697”. One package is sufficient for 33 days.

Tenuate 75mg

Tenuate 75mg oral tablets are the most popular among obese people. Taking the ER version of Tenuate can actually be safer and more effective than intake of IR tablets.

This is because the slow release of the active substance throughout the day helps to:

  • maintain a stable plasma level of Tenuate;
  • reduce the likelihood of adverse effects occurring.

The main advantages of Tenuate 75mg, compared to Tenuate 25mg, are as follows:

  • Reduction in frequency of intakes.
  • Only one 75 mg tablet per day.
  • Extended effect.
  • Works more than 24 h.
  • Good tolerability.
  • Fewer side effects.

Perhaps you may have lost weight once or many times in the past and now are aware that keeping it off proved to be difficult. Take control of your hunger and weight with Tenuate 75mg.

All the above factors increase the patients’ adherence to the treatment and make weight loss more comfortable and easy.

Notwithstanding all the benefits, Tenuate 75mg is not devoid of certain disadvantages, such as:

  • The risk of toxicity upon fast release in case when tablets are split.

The use of Tenuate may cause mild side effects in a small number of patients. At the beginning of therapy, patients most often experience headache, diarrhea, abdominal discomfort, or nausea.

Most adverse effects of Tenuate 75mg are mild to moderate and do not require the treatment discontinuation. If the woman becomes pregnant during the obesity treatment, she must stop using these diet pills and consult a doctor.

Tenuate side effects

Tenuate use in the recommended dosage is well tolerated and it does not cause side effects neither in adults, nor in adolescents.

Nevertheless, a few patients can develop adverse reactions when using this anorectic. Herewith, do not refuse to use this effective anti-obesity drug.

Many of Tenuate side effects are transient, mild or moderate, and disappear on their own without additional treatment.

When treating obesity, the most common side effects are the following gastrointestinal disorders:

  • nausea and vomiting;
  • constipation and dry mouth;
  • abdominal discomfort and unpleasant taste in the mouth.

These undesirable effects are usually observed in the first few weeks of using Tenuate and they disappear as the therapy continues.

The development of severe Tenuate side effects can be caused by the following factors:

  • abuse of anorectic;
  • combination of Tenuate with other drugs.


Tenuate abuse

As mentioned, the active substance of these weight loss tablets is a CNS stimulant Diethylpropion, which is very similar to Amphetamine in its action.

Exceeding the recommended daily dose of Tenuate leads to an overdose and development of drug dependence and pharmacological tolerance.

The patient may develop side effects of the central nervous system after the abrupt discontinuation of Tenuate, which usually manifest as:

  • depression;
  • sleep disturbances;
  • nervousness and agitation;
  • increased fatigue and sweating.

Combination of Tenuate with other drugs

It is believed that the mechanism of Tenuate action is based on stimulating the central nervous system and increasing blood pressure.

Therefore, combined intake of this anti-obesity drug with other anorectic agents or with MAO inhibitors may lead to the appearance of such side effects of the cardiovascular system, as:

  • elevation of blood pressure;
  • palpitations and chest pain;
  • heart rhythm disturbances (arrhythmia, tachycardia).

Tenuate may decrease the effectiveness of medications used to treat diabetes (insulin, glimepiride, and repaglinide). Decrease in hypoglycemic effect may increase blood sugar level and cause such adverse events as skin itching, blurred vision, or constant thirst.

Consult a doctor before combining Tenuate with any medications. In the event of severe adverse reactions, the use of this drug should be discontinued.

In order to avoid or minimize the occurrence of Tenuate side effects, adhere to the recommended dosing regimen of this drug during the entire period of obesity treatment.

Tenuate reviews

In search of the best means for losing weight people are trying to compare Tenuate and other pills and supplements, based on real patients’ reviews. However, it is important to keep in mind that bodies and health conditions of different people differ and it is impossible to judge medications based only on someone else’s opinion.

In accordance with many user reviews, Tenuate has a high therapeutic effect:

  • Appetite suppression throughout the day.
  • Stable weight loss.

Clinical studies confirm these facts. Tenuate reduces Body Mass Index in a stable manner, which results in lowering of risks for obesity-associated diseases.

According to clinical trials, and patients’ reviews, 25mg Tenuate and 75mg Tenuate Dospan pills are tolerated well. Side effects do not occur often and usually at the beginning of the obesity treatment only.

Patients using Tenuate, as well as other powerful appetite suppressants, most often complain about:

  • Anxiety,
  • Nervousness.
  • Excitement,
  • Dry mouth.
  • Dizziness,
  • Problems with falling asleep.

Not all patients lose weight with Tenuate and not every one of them believes that the benefits of the drug exceed the risks of side effects. Disputes about this drug also continue in the government regulatory agencies of different countries.

According to them, the risk-benefit balance of Tenuate is:

  • Positive – in the US
  • Negative – in Europe

Tenuate price

Tenuate is just as pharmaceutical product, as any other medicine. The price of Tenuate can differ greatly.

Today, this slimming medication is available for sale in different countries of the world, and its price in each of these countries is different.

Besides, the cost of the drug varies depending on:

  • Pharmacies where it was purchased.
  • Type of health insurance that you have.

Before you begin treating obesity, you can ask the doctor where you can buy cheap Tenuate. Yet not all doctors are aware of prices for weight loss drugs. Perhaps, you will have to do your own research.

You can choose a pharmacy that offers the lowest prices for Tenuate pills. You can visit the nearest pharmacies and talk with the pharmacists. However, it’s not always convenient, because it is obviously not an easy task to visit all the local drugstores.

Many people choose to purchase Tenuate online as a way to cut costs and save time. You can quickly and easily place your orders and this does not oblige you to leave your house or office.

However, you should be very cautious and search for reviews about the place, which you choose to deal with.

Getting back to the price, it differs depending on the package size. The larger the package, the lower the price of one tablet.

The anorexigenic drug is supplied in packs of different sizes:

  • 100 tablets
  • 250 tablets.

And, logic, the cost of pills depends on the strength of the pills.

The price of one Tenuate Dospan 75mg pill is lower than the cost of three 25mg tablets. The dosing frequency of such tablets is different, even though the daily dose is the same – 75 mg. One 75mg tablet should be taken once a day, in the morning. Tablets with the minimum dose should be taken three times a day.

Tenuate generics

The market of drugs for the obesity treatment offers Tenuate generics, as well. Their availability improves competition in the market and provides consumers with additional drug options to choose from.

If we consider buying the slimming drug only in terms of saving money, it is most profitable to buy Tenuate generics. The price of such drugs is lower than the price of a branded medication. As a rule, generics are sold under the name Diethylpropion.

Where to buy original Tenuate

  • If you live in the US, you can get a prescription for these pills from your doctor. In the US pharmacies, you can find brand Tenuate, as well as its generic versions.
  • If these diet pills are not available in the local pharmacies, you can opt for online purchase of these pills. Before you pay for the order, make sure that this drug can be delivered to the country of your residence.

If you were planning to buy Tenuate Retard online, and the pharmacy does not accept an order for its delivery to your city, you can try to find its generic versions.

American pharmacies sell several Tenuate generics, which contain 25 mg or 75 mg of the active ingredient Diethylpropion, just like the original tablets by the company Aventis do.

Tenuate cost can be higher than the price of its generics. If you want to buy diet pills at the lowest price – compare the cost of Tenuate and its generics in different pharmacies and take advantage of the best offer available.

Tenuate 25mg tablets are available in the USA. Previously they were available in Europe, but now are not sold in this part of the world. The American supplier of weight loss tablets is a pharmaceutical company Actavis.

Price of Tenuate 25mg tablets varies depending on the country in which you make your purchase and on the suggested prices of the selected pharmacy. Purchase of cheap Tenuate 25mg tablets helps to reduce the cost, but not the effectiveness of obesity treatment.

If you want to save even more on treating obesity, buy a generic of Tenuate 25mg tablets. Just as Tenuate, its generic drugs contain 25 mg of the active substance Diethylpropion, but they are cheaper than the branded drug.

In the USA, three different companies offer three generic drugs of Tenuate 25mg pills.

Diethylpropion 25 mg by Lannett «LCI» / «1475»


  • Aidarex Pharma,
  • Bryant Ranch Prepack,
  • NuCare Pharma,
  • Proficient Rx LP.

Diethylpropion 25 mg by KVK-TECH «К 44»


  • Aidarex Pharma,
  • A-S Medication Solutions,
  • PD-Rx Pharma,
  • Unit Dose Services.

Diethylpropion 25 mg by Patheon «Watson 783»


  • Actavis,
  • Apotheca,
  • A-S Medication Solutions,
  • Blenheim Pharmacal,
  • Bryant Ranch Prepack,
  • Keltman Pharma,
  • NuCare Pharma,
  • PD-Rx Pharma,
  • Physicians Total Care.

If you buy Tenuate without medical insurance and are forced to pay its full cost, better find out the price of generic Tenuate 75mg versions.

Two generics, available in the US, are produced by two different companies, such as:

  1. Lannett
  2. Patheon

Tenuate 75 mg tablets produced by these companies are available in brick-and-mortar drugstores under the non-proprietary name Diethylpropion.

Pill Identification

Diethylpropion 75 mg pills by Lannett Company Imprint «LCI» / «1477»


  • Aidarex Pharma,
  • A-S Medication Solutions,
  • Bryant Ranch Prepack,
  • PD-Rx Pharma,
  • Preferred Pharma,
  • Proficient Rx LP.

Diethylpropion 75 mg pills by Patheon Pharma Imprint «Watson 782»


  • Actavis,
  • Apotheca,
  • Blenheim Pharmacal,
  • Bryant Ranch Prepack,
  • Keltman Pharma,
  • PD-Rx Pharma,
  • Physicians Total Care,
  • Preferred Pharma,
  • Rebel Distributors.

If Tenuate (or its generics) is not available at a local pharmacy and ts delivery is impossible to your country, you can check out other slimming medications, like Phentermine or Sibutramine to assist your weight loss.

Nevertheless, don’t forget that any RX weight loss medication requires a preliminary health check and a properly developed and observed weight loss program.

History of Tenuate in Europe

In the UK, Germany, Spain and other European countries, the active ingredient Diethylpropion is better known under the generic name Amfepramone.

In the second half of the XX century, Tenuate brand was very popular in Europe, and today it is almost unknown to Europeans. In the late 90’s, all medicines that contain Diethylpropion were withdrawn from the European pharmaceutical market.

As a result, the sale of Tenuate in the UK, Germany, Spain and other European countries was terminated. In the US, however, this medicine is still available for sale.

  • American supplier of Tenuate diet pills is Aventis Pharma.
  • European supplier of Tenuate was the company Marion Merrel Dow Ltd. (part of Aventis today).

In different European countries, Merrel Pharma was selling Tenuate under similar sub-brands:

  • Tenuate Dospan in the UK
  • Tenuate Retard in Germany.

Merrel also promoted this drug under other original brands.

For example, in Spain Tenuate was not commercialized, yet in Spanish pharmacies you could buy Delgamer pills that contained the same dose of Diethylpropion, as Tenuate tablets (Dospan and Retard) contain.

Some online pharmacies offer the opportunity to order Tenuate delivery to any country in the world. Still, before you buy Tenuate pills online in Germany, UK, or Spain, make sure that they can be delivered to your city.

History of Tenuate in Canada

Tenuate that is sold in Canada are the same tablets for the treatment of obesity that are available for sale in the US and in other countries.

  • Tenuate is available in tablets containing 25 mg or 75 mg of Diethylpropion Hydrochloride.
  • Daily use of a 75mg dose suppresses cravings for food and helps people lose weight.

However, Tenuate sold in Canada and the same drug sold in the US do have some differences.

Tenuate in Canada

  • Is prescribed for patients 12 years of age and older.
  • Is used to treat excess weight or obesity.
  • Is supplied by Sanofi-Aventis.

Tenuate in the US

  • Is not approved for patients younger than 16 years of age.
  • Is used only for the treatment of obesity.
  • Is supplied by Actavis.

Today, Tenuate is available for sale in Canada and Europe. Medical agencies in these countries have studied new information about high risks of cardiovascular side effects. They concluded that consumers will not benefit from the use of Tenuate, and the drug was withdrawn from the market.

You can still buy Tenuate in the US. You will also find generics of this drug by Lannett and Avanthi companies. The FDA believes that the benefits of Tenuate in weight loss exceed potential risks.

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