For those, who already know about the basics of Phentermine and came in search for most frequently asked questions, get your answers right now without having to read the entire “story”.
If you’re new to this weight loss medication, you might think that you know everything about Phentermine that you need to know and will pop the pills and watch those kilos woosh away every day.
Well, there’s more to that, and knowing what this drug does to your body, as well as envisaging your weight loss progress can help you get this fat-fighting campaign to a point that you’ve never reached before.
Each and every question that you have, and even those that you didn’t have until now – we’ve covered them all in this Ultimate Guide on Phentermine-containing drugs.
Phentermine 37.5 mg
As you surely know, Phentermine is one of the most popular anti-obesity drugs widely used when treating overweight or obesity.
It helps to get what you really deserve – a slim and healthy body without hunger pangs.
So, what is Phentermine 37.5 mg?
It’s an anorectic drug, prescribed to treat:
- overweight: BMI 27 – 29.9;
- obesity (class 1): BMI 30-34.9;
- obesity (class 2): BMI 35-39.9;
- extreme obesity (class 3): BMI 40 or more.
At that, Phentermine is recommended for the treatment of overweight people only when they have one or more weight-related comorbidities, like dyslipidemia, hypertension, obstructive sleep apnea, or dysglycemia.
If you’re interested (and you should be, since you’re planning to put it into your body), here’s some info about what drug class Phentermine is.
It belongs to a drug class called:
- anorexigenic drugs.
All drugs of this class are related by their chemical structure and have much in common.
Even though they do have some similarities, they are not identical completely.
Anorectics activate a part of the brain that controls hunger and satiety.
Their anorectic effects include stimulation of the central nervous system, hunger decrease, as well as increase in blood pressure.
The active substance in a variety of slimming pills is Phentermine Hydrochloride (HCl).
Let’s take, for example, diet pills, which contain 37.5 mg of the active substance.
Even though the shape, size, and color of the pills differ, their therapeutic effect is the same, namely decrease in food cravings.
Ok, let’s get it straight, you can buy either Phentermine HCl 37.5mg oral capsules (which usually come in orange or blue / white capsules), or you can find Phentermine HCl 37.5 mg oral tablets (usually white with blue specks).
It doesn’t really matter!
Just so you know, this drug is produced by a variety of pharmaceutical companies, such as:
- KVK Tech;
Now let’s check out the indications for the use of Phentermine
US doctors prescribe Phentermine weight loss drug for the treatment of obesity in:
- Teenagers of 16 years and older
- Adults under 64 years (included).
Elderly US patients aged 65 and older are very rarely prescribed with Phentermine.
Phentermine Mechanism of Action
Phentermine is believed to promote satiety and suppress appetite by selectively activating noradrenergic and dopaminergic receptors, located in the hypothalamus.
So, this anti-obesity drug works in the brain.
It will stimulate the brain cells by changing the level and activity of the mentioned neurotransmitters – substances that transmit signals from one brain cell to another.
This stimulating action ensures the following effects:
- Food cravings decrease;
- Hunger is suppressed during the day.
These slimming pills do what most of us really need – suppress the appetite and help us consume less food.
This makes our body burn the stored fats, while we do not have to fight our hunger at all.
Phentermine Tablets vs Capsules
As already mentioned you can find this slimming drug in both variants, caps and pills.
So what’s the difference between capsules and tablets of Phentermine.
… short insight into the history of medicines making.
Long time ago, people used to take medicines in form of liquids and powders.
Then, chemists learned how to press the powder into pills, adding some auxiliary substances into them.
And THIS is how tablets were born.
… the end.
Tablets or pills are the most common pharmaceutical form of drugs in the world.
Phentermine pills contain medical ingredients in a pressed form for oral intake.
As you probably know, these pills have been used for the anti-obesity treatment since 1959 and managed to gain a high popularity among those, who strive to lose excessive weight.
When you take a Phentermine pill orally, it takes some time for the active substance to be absorbed into blood, because the tablet needs to swell first, then it disintegrates and releases the active substance.
Now THIS is one of the disadvantages of this dosage form.
However, the good thing about the pills is that you can divide these into two pieces, thus controlling the dosage (you cannot do this with capsules).
Many overweight or obese patients believe that it is much easier to swallow Phentermine capsules, than tablets, but it depends on your personal preferences.
Since you should not open the capsules, these are produced in different dosages, e.g. 15 mg, 30 mg or 37.5 mg.
Just so you know, in the US pharmacies, you will more probably find 37.5 mg capsules (Adipex-P) containing Phentermine HCL.
Well, as you can see, there is no much difference between Phentermine capsules and tablets.
So you really don’t need to search for one dosage form, when you have the other, because the action remains the same.
Weight loss pills can contain:
- Phentermine 8 mg
- Phentermine 15 mg
- Phentermine 30 mg
- Phentermine 37.5 mg
- Phentermine 40 mg
The appetite suppressing effect is dose-dependent and varies from patient to patient.
Regardless of the dose, the optimal effect is achieved when you take the drug every day at about the same time.
Typically, one 30mg (37.5 mg of HCl version) dose once a day in the morning is used at the beginning of the obesity treatment.
Most patients do not need a dose adjustment and use the same dose during the entire treatment course.
Your dosage, though, can be adjusted, based on the response to the initial dose, the severity of obesity and the health condition.
How to Use Phentermine 8 mg
The lowest Phentermine dose of 8 mg is intended for those, who struggle with night cravings mostly.
If the use of Phentermine 37.5mg does not suppress appetite throughout the day, you may be advised to take one 8mg pill before (30 minutes) each main meal.
However, if the AM dose helps you survive through the lunch time without extreme hunger, you can switch to taking it just twice.
In fact, you can adjust the schedule of taking the 8mg pills depending on your body response.
There’s just one thing to keep in mind… Avoid taking the last 8mg pill late in the evening, or you might lose sleep.
How to Use Phentermine 15 mg
As a rule, this dose is used once a day, in the morning, with or without food, and with a glass of water.
Looks simple… but!
When this dose does not provide the desired effect and you don’t want to waste your money, you have 2 options:
- Ask your doctor, whether you can take two 15mg Phentermine pills at once, in the morning.
- Ask your doctor, whether you can take one 15mg Phentermine pill in the AM, and the other by noon – to extend the effect.
- Save the 15mg pills for later, to ensure a gradual exit from the course and avoid possible withdrawals.
The last option will help you save money, because you will not have to dispose the unused 15mg pills.
Instead, you will benefit from their use at the end of the course and make the exit smooth.
How to Use Phentermine 30 mg
The 30mg dose of Phentermine should be taken once a day in the morning (or evening, if you have a night shift work).
Taking the dose at the same time every day is a good thing.
Thus, you ensure a consistent flow of the drug into your body every day.
Besides, you help your body get used to living-on-schedule, which can be quite beneficial for the weight loss.
Do not take more than one 30mg pill per day.
How to Use Phentermine 37.5 mg
Phentermine 37.5mg has almost the same dosing regimen, like the 30mg dose has.
Once a day, in the morning, without doubling the dose.
However! Those Phentermine 37.5mg pills that have a score-line can be divided in two halves and taken:
- Once a day, when the whole pill is too strong for you (i.e. severe side effects manifest).
- Twice a day (morning and noon), when the effect of the whole pill fades early in the evening and doesn’t help to fight night cravings.
Taking three halves of a Phentermine 37.5mg pill is contraindicated, since the total dose will amount to 56.25 mg of the anorectic agent.
It is dangerous to take such high doses of this drug.
How to Use Phentermine 40 mg
This is the highest dose of Phentermine in a single pill.
Take it only once a day.
If it causes adverse reactions, which are too severe and unbearable, ask your doctor to issue a prescription for a lower dose.
Or You can try to take it every other day.
How to Take Phentermine Properly
Taking Phentermine properly implies:
- Compliance with the dosing schedule
- Avoiding any damages to the pill/cap
- Taking the drug with or without food, depending on your preferences
- Avoiding late night administration of the drug.
One more important thing is to avoid recreational use of Phentermine.
Such mindless treatment can result in unexpected side effects, especially if you never checked your health to suit the use of this medication.
How Long to Use Phentermine
The funny thing is that you can use Phentermine long-term. ONLY IF you make breaks from its use.
1-2 months will be sufficient.
The main thing is not to forget that you need to keep working on your eating and exercising behavior during such pauses, as well.
You don’t want to waste all results that you have achieved and again start at the original weight.
This is how it goes:
- Phentermine for 3 months.
- 2-month break.
- Phentermine for 3 months.
- 2-month break.
How Long Does Phentermine HCl 37.5 Stay in Your System?
Knowing the half-life of your drug can be essential in a variety of life situations.
For example, if you need to take some other medications, such as antidepressants.
The half-life of Phentermine depends on the metabolism of every individual patient and ranges from 16 to 31 hours.
If you wonder, whether Phentermine shows up in a drug test, read the answer below.
Phentermine can be detected in your body.
This drug is found in the blood and urine for 1-4 days and in the hair – for up to 90 days after the last dose.
Keep in mind!
Until this weight loss drug remains in the circulatory system, it can interact with other medications you are taking.
To avoid drug interactions and not to alter the action of Phentermine-containing pills, inform your doctor about every single medication that you use, including dietary supplements, especially those that contain caffeine.
What are Side Effects of Phentermine Pills?
Daily doses of Phentermine 37.5 mg have long been used for obesity treatment, and usually cause mild or zero side effects.
However, unusual response of the body to the drug cannot be excluded, especially at the course beginning or when you increase the daily dose.
The list of Phentermine 37.5 mg side effects includes:
- high blood pressure;
- difficulty falling asleep and insomnia;
- abdominal discomfort;
- sexual dysfunction;
- urinary disorders.
- bad taste in the mouth
- dry mouth
- heart disorders
- change in libido
Some users reported hair loss on forums about Phentermine side effects.
However, it has not been proven that Phentermine-based pills cause this effect.
Unfortunately, this is not a complete list of side effects.
Yes, it is a lot longer and concerning, and you can read it in the package insert.
However, the incidence of severe side effects is rather low, which sort of calms down.
How Long Do Phentermine Side Effects Last?
Well, it depends…
Phentermine may cause short-term or long-term side effects.
Most often, users report of the short-term side effects, which pass with no treatment in a few days after the treatment initiation.
However, some side effects of Phentermine (e.g. insomnia, dry mouth and nervousness) may occur periodically or continuously throughout the entire anti-obesity course.
Since this slimming drug works in your brain, the side effects from the side of the central nervous system (CNS) are possible from time to time during your weight loss campaign.
The most common of these are sleeplessness and nervousness.
You can reduce the risk of sleeplessness by taking the diet drug only in the morning or within 1-2 hours after eating.
Abandoning coffee and coffee-containing drinks also reduces the risk of insomnia.
Unfortunately, it is impossible to predict, prevent or reduce nervousness on Phentermine.
However, clinical studies have shown that it occurs most often at the beginning of the course.
Your body needs about 7-10 days to get used to the drug action, and this is when the nervousness usually subsides.
As for the long-term side effects of Phentermine, these usually affect the gastrointestinal tract (e.g. dry mouth, unpleasant taste, nausea, and diarrhea).
Most users report that xerostomia is present during the entire course.
In rare cases, dry mouth persists even after the discontinuation of these weight loss pills.
To eliminate dry mouth, it is recommended to consume plenty of fluids (at least 1.5-2 liters of fluids per day)
It is advised to quench your thirst with still water, natural juice or unsweetened herbal tea.
Carbonated soft drinks will not help you solve this unpleasant issue.
Furthermore, most carbonated beverages contain caffeine, which may lead to dehydration and increase the risk of sleeplessness.
You can use special salivation-increasing tablets, as well.
The same, or some simple breath freshening products will help you eliminate bad taste in the mouth (just be sure to check the sugar contents in the mints).
If you have nausea, when you take the pills on an empty stomach, you can prevent it by taking the drug in the morning, within 2 hours after eating, or have a light “snack” along with the pills, like yogurt, half an apple, etc.
Phentermine may impair your sexual life, for example alter your libido or cause erectile dysfunction.
Typically, these Phentermine side effects are not dangerous for physical health, yet they definitely can be unpleasant.
At the end of the treatment course, you need to reduce the daily dose in a gradual manner.
This will help your body adapt to the fact that the drug ceases to stimulate the CNS.
Possible withdrawal Phentermine side effects are:
Phentermine Weight Loss Rate
Of course, knowing more about all the negatives that you can “feel” while on Phentermine, it is natural to ask “how much weight I will lose with Phentermine?”.
Well, you can notice your body weight reducing starting from the first day of the course.
As for the clinical data info, these confirm that you will usually notice a significant weight loss in the beginning of the weight loss treatment.
By the end of week 12, your weight loss will slow down, and might even stop completely.
It is a normal body response, as it gets used to the drug action.
The most successful model for weight loss is to alternate drug and non-drug anti-obesity therapy.
In other words, the end of a three-month course of Phentermine pills does not mean that you should stop keeping a balanced diet and exercising.
If you are planning to get back on the drug course for obesity after a break, you should proceed the same way, as you did during the course, i.e. watch your eating and maintain a high activity level.
Nutritionists claim that this weight loss model helps your body adapt to your new weight and prevent the weight regain.
Before we commit to a new lifestyle on Phentermine, we are definitely curious what results other users achieved.
Of course, when we evaluate the positive consequences, it helps us approach and achieve our goal.
Let’s be straight, as much as you would like it, you will not see immediate and impressive results.
Nevertheless, a correct use of Phentermine for 12 weeks should provide amazing weight loss results.
If you take it every day (or as your doctor says) at the same time and follow the dosing, eating and exercising recommendations, you may notice the obesity treatment results quite fast.
Phentermine: Week 1 Results
- You understand that you are truly capable of controlling your food intake.
- You lose 0.5 to 1 kilogram.
Phentermine: 1 Month Results
- You can further reduce the caloric value of your diet.
- You lose 2-4% of body weight.
Phentermine: Before and after Results
- You already know which diet works best for you.
- Your weight has decreased by 10-15%.
Unfortunately, there is no clear answer to the question how much weight you will lose exactly.
The results will always be differ in different people.
They depend on various factors, and primarily on:
- Metabolic rate.
- Severity of obesity.
- Chosen diet plan.
- Intensity of physical activity.
- Presence of any diseases that affect your weight (or taking drugs with the same side effects).
- The “amount” of changes that you made to your daily routine (i.e. if you were not consuming tons of food before the treatment, a slight decrease in portions usually does not provide high results)
It is always a great idea to consult with dietitians, trainers, doctors, and other experts in weight management before you begin taking Phentermine.
Results without exercise and/or diets may be low and unlikely to impress you.
However, if you do everything correctly and adhere to the weight loss plan, you will be losing weight, though slowly yet steadily.
Your waist size will decrease and the clothes will start fitting loose.
In addition, there will be changes that can not be seen with the eyes.
“Invisible” weight loss results of Phentermine use, which can provide a positive effect over your health, are:
- Blood pressure lowering.
- Cholesterol level improvement.
- Reduction of risk for diabetes.
If you need additional evidence that Phentermine does work, take new photos of yourself.
This will help you actually SEE the results with your own eyes.
Comparing your old photos to your progress photos can become a great motivation to continue your struggle with obesity.
OR you can calculate your Body Mass Index (BMI) before the course beginning.
You can compare your new BMI with your original BMI every week and easily assess your weight loss rate over time.
How Fast Do You Lose Weight on Phentermine?
The rate of weight loss depends on two factors:
- The body’s reaction to Phentermine
- The patient’s commitment to a comprehensive weight loss program.
You see, our bodies differ too much from each other.
Even the same body may respond to Phentermine in a different way in various time periods.
It is clear that patients with I or II degree of obesity are easier to achieve a healthy body weight than patients with III or IV degree of obesity, even if they lose the same number of kilos.
At that, people with more kilograms to lose usually lose more weight, compared to those, who have less excess fat.
DO NOT compare your results to other people’s results!!!
Avoid this mistake, because you risk to either lose motivation (if your results or lower), or start cheating and waste your chance (if your results are higher).
Just so you know, there are cases when Phentermine helped people lose 20-30 kg and more.
However, most obese people manage to lose at least 5-15% of their initial body weight.
So, while the drug helps most people, some report of no effects…
Your task during the first weeks of Phentermine use is to make sure that these weight loss pills are effective for you.
Not Sure, Does Phentermine Work Anymore?
Unfortunately, no one is safe from the situation when the body gets used to Phentermine action.
However, incorrect approach to diet may result in malnutrition.
If you went too far with your dietary restrictions on Phentermine, you will surely be hungry.
And this will not mean that the drug stopped working.
Review your nutrition and make sure that it is balanced, or ask a professional to help you develop a proper eating plan.
The main thing is NOT to up the dose on your own without talking to your doctor.
Does Phentermine Really Work?
It’s a normal thing to doubt the effectiveness of Phentermine.
Though, thousands of reviews of successful weight loss stories and a bunch of successful clinical trials definitely prove that the drug does really help people lose weight.
And here is what exactly Phentermine did for all those lucky and hardworking people, who managed to achieve their weight loss goals:
- Suppressed the strongest hunger.
- Helped reduce food intake starting from the first day of treatment.
- Accelerated the fat burning process.
- Assisted in a stable weight loss and physical appearance improvement.
These are the average results, determined during clinical trials.
That’s what helps Phentermine maintain its position in the list of the best drugs for weight loss.
How Long Does Phentermine Work?
Now it’s time for some bad news…
Unfortunately, the weight loss progress often slows down in a few weeks, because your brain gets used to what Phentermine does.
It usually takes up to 12 weeks for this to happen.
Logic question here is “Can I take Phentermine longer than 12 weeks, if I fell that it still works?”
Well, yes, you can.
Your doctor needs to approve the long-term use and assess your health condition and risks for addiction to the drug.
ALWAYS!!! Follow your doctor’s recommendations for dosing and the weight loss program and better take at least a 1-2-month break from Phentermine after every 3-month course.
Does Phentermine Stop Working?
“My Phentermine is not working anymore” – many people leave such reviews.
As mentioned above, your brain gets used to the drug action, hence a weaker appetite suppression.
Never forget! It is a short-term treatment course, and you need to get the best result of it.
What to Do if Phentermine Stops Working?
If Phentermine doesn’t work, don’t panic and don’t stop the treatment!
The appetite suppressing effect can disappear after 10-12 weeks, yet not when the drug is used only for 4-6 weeks.
If you feel that diet pills do not work the way they should work, you might be making some mistakes.
As a rule it’s all about the dosage.
And you can take some steps to keep Phentermine working.
How to Make Phentermine Work Again?
Dose adjustment is a fast and the best way to get Phentermine to work again.
Using the maximum dose can help restore the appetite suppressing effect, yet only if you were using medium doses previously.
What if the Maximum Dosage is no Longer Effective Either?
Try switching to a different dose and dosing regimen, i.e.:
- Phentermine 8mg
- Three times a day
This can help improve the effect of the drug.
Or you can try to trick your body and stop taking it for about 4 days, and then start taking it again, just like you did before.
Many users say that this tactics helped them boost Phentermine action again.
Will Phentermine Work without Exercise?
You see, Phentermine should be used as an assistant.
Yet, you need as many assistants in your weight loss campaign, as possible. That is, of course, if you are truly willing to lose weight and change your life to a healthier and fitter side.
So, to get the maximum benefit of Phentermine, your weight loss “team” should consist of:
- Strong motivation
- Balanced healthy nutrition (Upgrade this assistant with a Food Diary – you won’t regret)
- Higher level of physical activity
- Adequate body hydration
- Sufficient sleep
- Cosmetic procedures (To help your skin adjust to new body volumes)
- Determination to keep going
- Great support team.
Phentermine alone will not help you achieve your goal and maintain the result.
It’s a real war against the excess fat that you have to win!
And you need to use an army to do that.
So tick all enlisted measures, use them, and THIS is indeed the best way to use Phentermine for maximum results.
Phentermine will reduce your appetite, and switching to a weight-loss eating plan is 80% of success.
If the 80% efficiency is sufficient for your goals, you can continue without exercising.
If you want all 100% of Phentermine course, you will have to exercise.
Because exercising will help you to:
- burn calories
- create the required energy deficit
- gain muscles, which burn fat even at rest
- improve your body forms
- lower the chances of saggy skin
Do you need any other pro’s of exercising while on Phentermine?
If these are not enough, then do your best with the eating and pray for awesome results.
By the way, exercising does not necessarily mean high intensity exercises (though they certainly help burn more fat within shorter time).
Jogging or walking burn calories effectively and help lose weight, as well.
What Happens When You Stop Taking Phentermine?
Once you stop using the drug, it no longer stimulates your central nervous system.
When the liver and kidneys remove the drug from the body, the hunger will return.
You might not have the same difficulty in controlling the food intake, though for some people this though challenge comes back with a vengeance (especially if you didn’t use the 3 months to develop new healthy eating habits).
How to Stop Taking Phentermine?
Never stop using Phentermine cold turkey, even if it has stopped working completely (unless it caused severe side effects).
You need to reduce the daily dose at the end of the treatment course.
The minimum effective dose of Phentermine is 8 mg.
A gradual decrease in the daily dose will help:
- The brain to adapt to the disappearance of the appetite suppression effect.
- Minimize the risks of withdrawal symptoms.
This step is important, because Phentermine may cause physical and psychological dependence.
Long-term abuse of Phentermine or any other CNS stimulant may cause changes in the brain function and lead to serious health problems, including memory loss and severe mental illness.
If any unpleasant sensations manifest after the pills discontinuation, inform your doctor and follow his advice to eliminate them.
Weight Gain after Stopping Phentermine
Many people find it difficult to defeat hunger after the end of the course, and start eating more.
Weight regain is quite a frequent problem in the pills users.
You can avoid weight gain after stopping Phentermine use, or lessen the amount of regained kilos.
Just continue with dieting and exercising, and find a VERY strong motivation, which will help you cope with the cravings.
Which Diet Pills Work Like Phentermine?
Modern market offers several effective weight loss drugs, which contain the active ingredient Phentermine hydrochloride.
People often buy Adipex (Phentermine), which is why many users wonder whether there is a difference between Adipex and Phentermine Hydrochloride.
Both drugs are intended for people wishing to lose weight and are made in tablets and capsules for oral use.
A significant difference between these slimming drugs is that Adipex is manufactured only at a dose of 37.5mg, while Phentermine Hydrochloride has different dosages: 8 mg, 15 mg and 30 mg.
The latter is convenient for patients who have contraindications to the use of the highest dose of Phentermine HCl.
Adipex, K 25, Duromine and Metermine are diet pills that work like Phentermine.
They all contain Phentermine
Which of them work better?
Since they all contain the same ingredient and are each other’s analogues, they work the same way.
Brand products work no better and no worse than their generics do.
Besides, the market is flooded with a variety of drugs to treat obesity, which have different mechanisms of action.
Some of them may be better than Phentermine for you in particular, yet not for everyone who uses it.
How to Use Phentermine Safely
Safety comes first – we know it! Safety with Phentermine has several levels:
- Sharing your health details with your doctor and making sure that the drug is not contraindicated to you.
- Taking the drug. For oral use only and no chewing or crushing, if not allowed!
- Observing the dosing schedule and doctor’s recommendations (do not increase the dose!)
- Self-evaluating your overall health when using the drug, i.e. checking the heart rate, blood pressure and addressing for medical care if needed.
Use Phentermine For a Limited Period of Time
As already mentioned, it is recommended to use these weight loss pills up to 3 months in a row.
And you can continue using the drug only if your doctor recommended further treatment after examining your current health condition.
Phentermine capsules must not be administered in people:
- with diagnosed cardiovascular disease or history of cardiovascular events.
- prone to alcohol or drug addiction.
- with hyperthyroidism (common symptoms: rapid heart rate, abnormal muscle weakness, emotional hyperexcitability, nervousness, irritability and increased appetite).
- with various forms of glaucoma (secondary, congenital, open-angle, angle-closure).
- with mental disorders (including agitated state without depression).
- pregnant women (category X) and nursing mothers.
Phentermine Drug Interaction
One of the most important factors that can have a significant impact on the effectiveness of anti-obesity therapy is drug interaction of Phentermine with other medicines.
Overweight and obesity are often associated with serious concomitant diseases that require a separate treatment.
While the weight loss is one of the main tasks for many obese people, they often need to take other drugs that help to reduce the severity of comorbidities.
Such diseases as cardiovascular diseases, high blood pressure, and diabetes require special treatment.
Use of drugs to treat these pathological conditions together with Phentermine may cause dangerous drug interactions and reduce the effectiveness of the anti-obesity treatment.
Herewith, a significant reduction of weight helps the person to get rid of or control the most of obesity-related diseases and improve their health.
To reduce the risk of negative Phentermine drug interaction, use caution and recommendations on the anorectic use.
A particular attention should be paid to Phentermine ability to interact with the following medications:
- Monoamine oxidase inhibitors
- Oral hypoglycemics and insulin
- Adrenergic neuron blocking drugs
- Alcohol-containing medications.
Data from clinical studies have shown that monoamine oxidase inhibitors (linezolid, selegiline, and phenelzine) increase the pressor effect of sympathomimetics, including Phentermine.
Combined use of these medicines raises blood pressure that causes arrhythmia, headache and hypertensive crisis.
To avoid serious disorders and drug interaction, Phentermine should be taken only two weeks after the cessation of MAO inhibitors.
Treatment of diabetes is no less difficult than the obesity treatment.
When treating diabetes, people take insulin and oral hypoglycemics.
If Phentermine is used only with oral hypoglycemics or only with insulin, changes in blood sugar level are expressed not so much as it is when combining the weight loss pills with both anti-diabetic medicines.
Studies have shown that the drug can affect the action of the oral hypoglycemics and insulin.
In such cases, users may need to take lower doses of insulin or hypoglycemic drugs.
Hypertension is considered a risk factor for coronary heart disease, as well as the main cause of vascular diseases of the brain.
A number of clinical studies has shown that Phentermine can interact with adrenergic neuron blocking drugs and reduce their hypotensive effect.
Therefore, to achieve the needed antihypertensive action and reduce the risk of cardiovascular events, the Phentermine dose should be lowered.
Alcohol is often used in the pharmaceutical industry.
It provides a bactericidal effect and is used as a preservative and solvent in pharmaceutical preparations.
However, alcohol itself is a strong CNS stimulant, and furthermore, it enhances the anorectic effect of this slimming medication.
Combined use of alcohol with Phentermine pills leads to the CNS side effects, including insomnia, headache, euphoria, psychosis, and dysphoria.
In order to avoid undesirable drug interaction with alcohol-containing medical preparations, carefully study the composition of all medicines that you use together with this anorectic.
If you find out that any of them contains alcohol, better suspend their use.
When you finish the anti-obesity course, you can resume the use of alcohol-containing medicines.
Although the combined use of Phentermine with alcohol-containing drugs is unlikely to result in a clinically significant interaction, it can still cause a lot of discomfort and adverse reactions.
It is especially dangerous to combine these slimming pills with alcohol-containing drugs, because the consequences can be severe and unpredictable.
Alcohol affects people in a different way:
- some people experience drowsiness and lack of energy, and relax,
- others vice versa – great excitement and high blood pressure.
This condition increases the workload of the heart, which can lead to cardiovascular events (heart failure, bradycardia).
Adverse drug interaction of Phentermine with alcohol can be a reason for canceling this appetite suppressant and termination of the anti-obesity therapy.
Phentermine HCL vs Phentermine Resin Complex
Phentermine HCL pills dissolve easily and quickly in any water-containing liquids, including the gastric juice, which ensures a fast dissolution of pills and fast passing of the active substance into the blood.
Phentermine resin complex pills dissolve gradually under the influence of ions, present in gastrointestinal fluids, and their controlled and continuous dissolution occurs for up to 14 hours.
Difference between Phentermine resin and Phentermine HCL is quite essential.
However, the weight loss results are approximately equal in people taking different forms of the drug.
Some people, though, can benefit from the use of HCL or resin complex.
Still, it is impossible to come to a certain conclusion on whether one form is better than the other.
Phentermine and Other Anorectics
Now that we know quite a lot about Phentermine, but what it there are some alternatives…
Well, there do exist other drugs in the same class with Phentermine, and these are as follows:
Usefulness of some of the listed anorectics in treating obesity is controversial.
Some of them, for example Sibutramine, are not currently available on the pharmaceutical market.
It has been proven that Sibutramine causes severe side effects, much more often than Phentermine does.
Class action lawsuits were filed against many manufacturers of anorectic drugs.
Some legal proceedings are still pending.
Anorectic drugs that were found to be unsafe have been withdrawn from the market.