One of the most common side effects of Orlistat is fecal incontinence and diarrhea. These gastrointestinal side effects are very pronounced at the initial stage of obesity therapy.
Due to these side effects, obese people who regularly or periodically experience constipation can gain additional benefit from Orlistat use.
If obese patient experiences constipation because of inadequate nutrition, gastrointestinal diseases, neurological risk factors or medication use, recurrence rate of constipations will be significantly reduced after the start of using Orlistat.
When using Orlistat for chronic constipation treatment, remember that this drug is approved only for obesity treatment. In 2005, a group of researchers studied Orlistat effect on constipation in patients taking opioid drugs.
The study results have shown that Orlistat can really relieve constipation caused by opioids.
However, this data is insufficient to approve Orlistat as a treatment of drug-induced constipation.
It is also important the fact that Orlistat causes constipation in some patients.
- Clinical trials of Orlistat have shown that patients with inflammatory bowel diseases experienced constipation.
Effect of Orlistat (Xenical) on the relief and occurrence of constipation has been studied for many years.
Despite the numerous reviews about the ability of Orlistat to alleviate constipation, the researchers believe that this drug should not be used off-label.
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