Metermine earned its popularity for a good reson – it does work great for weight loss. If you know nothing about this medication and are planning to use it, this article is for you.
We did our best to dig it out of every source that we found, including the researches, reviews and patients’ opinions, and give you this Ultimate Guide on Metermine.
Those, who want to know it all, enjoy your reading and enlightment
Metermine is a brand name of Phentermine weight loss medication.
The rightholder of the brand name Metermine is iNova Pharmaceuticals.
This company produces Metermine oral capsules, containing 15mg, 30mg and 40mg of Phentermine anorexic agent.
This medication was listed in Australian Register of Therapeutic Goods in July 2004.
Packages with 3, 7 and 30 Metermine capsules have been available for sale in Australian pharmacies for over 10 years.
- Pharmacological group of Metermine – amphetamine derivatives.
- Therapeutic group of Metermine – weight loss medication.
Marketing status of Metermine – Prescription Only.
Australian hospitals, specializing on obesity treatment, usually get packages with 300 Metermine capsules.
This medication is available in Australia by prescription only.
Metermine is not the only medication containing Phentermine, which is available on the international pharmaceutical market.
In dozens of the world countries, you may find Metermine generic drugs that contain Phentermine anorexic agent just as Metermine.
In the UK, Metermine generic is available under the brand Ionamin, in New Zealand – under the brand Duromine, and in the USA – under the brand Adipex and nonproprietary name Phentermine Hydrochloride.
Indications for Metermine use
Metermine capsules are prescribed to teenagers of 12 years and older, as well as to adults and elderly patients:
- With BMI 25 to 29 (only with related risk factors)
With BMI 30 and higher (class 1,2 or 3 obesity).
Metermine mechanism of action
Pharmacological effect of Metermine (Phentermine) is believed to be similar to that Amphetamine (though it is seriously questionable) and thus the sale of Metermine weight loss pills without a prescription is illegal.
Controlling Health Authorities of several countries banned to use medications that contain Phentermine for obesity treatment (for instance, some of the European countries).
Active substance Phentermine acts on the brain areas that participate in regulation of hunger and appetite.
Stimulating dopaminergic, noradrenergic and partially serotoninergic nervous system, Phentermine suppresses the appetite and prevents overeating.
It is not difficult to get a prescription for Metermine weight loss pills.
If obesity is not accompanied by a severe disease, most likely the doctor will prescribe Metermine to a patient.
Patients, who are not allowed to use this medication or those, who don’t want to undergo a medical examination, should use weight loss pills available without a prescription.
Precautions & Contraindications
Metermine capsules may cause psychiatric side effects; therefore, they must never be taken by obese or overweight patients, who suffer from depression, anxiety, drug dependence or any other mental disorder.
Metermine is contraindicated to other groups of patients, including those, who have glaucoma or a history of cardiovascular disease.
It is important to know that Metermine weight loss pills can greatly affect the blood pressure and heart work.
Therefore, common Metermine contraindications are associated with the following diseases and pathologies:
- Noises and other abnormalities in the heart.
- Hypertension of pulmonary artery.
- High blood pressure.
- High blood pressure in the eyes (glaucoma).
- Change in the heart rate and rhythm.
- Brain dysfunction, caused by blood vessel disease.
If patients have either of these diseases, they must not use Metermine weight loss pills, since it can cause irreversible necrosis of heart muscle or an acute cerebrovascular accident.
Overweight patients often suffer from heart disorders.
Therefore, they should tell the doctor about any painful sensations in chest or heart before and during the use of Metermine diet pills.
Metermine and mental diseases or depression
Metermine slimming pills must never be used in severe mental diseases and depression.
You already know that the active substance of Metermine is Phentermine, which can affect the brain functions.
Moreover, depressive disorders require the administration of antidepressants or other drugs affecting a patient’s mind.
Metermine for pregnant or breastfeeding women
Metermine can cause a negative effect on a child development, so these diet pills are contraindicated to pregnant and breastfeeding women.
These diet pills have many contraindications; however, most obese patients are not contraindicated to use them.
When using Metermine, people should keep in mind an important thing: these are effective and thus powerful weight loss pills.
If a patient follows all the medical recommendations, he can use Metermine and keep losing weight in a stble manner.
If you want to get rid of excess kilos using Metermine weight loss pills, but you have never used this appetite suppressant, carefully read the full list of contraindications, included in the package insert.
Metermine doses and dosing recommendations
You can find this medication in form of capsules of equal size and shape, containing different amount of active substance Phentermine as a resin. Metermine strengths differ: 15mg, 30mg and 40mg.
The drug dosage is prescribed to patients according to their age, severity of obesity and common state.
WARNING!!! Do not change the dosage on your own!
If a prescribed dosage does not suppress the appetite, you should consult a doctor.
Only the doctor can change the dosage of Metermine several times during anti-obesity therapy.
To avoid confusion, Metermine manufacturer – iNova Pharmaceuticals (Australia) produces Metermine capsules of different color, depending on the dosage.
- Metermine 15mg – the shell consists of two halves of grey and green color.
- Metermine 30mg – the shell consists of two halves of grey and reddish-brown color.
- Metermine 40mg – the shell consists of two halves of grey and orange color.
Moreover, for people who cannot recognize colors, each capsule has a clear imprint indicating the dosage.
It is recommended to use Metermine capsules right before or during a meal. Patient, suffering from obesity can be advised to use:
- One Metermine 15mg capsule – once daily
- One Metermine 15mg capsule – two times a day
- One Metermine 30mg capsule – once daily
- One Metermine 40mg capsule – once daily
The maximum recommended Metermine dose for teens is 30mg.
Elderly patients should take Metermine only under a doctor’s supervision.
Metermine 15 mg
Metermine 15mg is a minimal dose, which can be used during anti-obesity therapy.
Most patients, who suffer from obesity, can take any dose of Metermine. However, there are categories of patients that are recommended to use a minimal dose – Metermine 15mg, such as:
- Young people;
- Patients with comorbidities;
- Elderly people.
Obese patients of 12 years old and older can take Metermine weight loss pills.
Typically, young people of 12 to 18 years old do not suffer from a severe obesity, so they do not have great problems with metabolism.
Therefore, Metermine 15mg is a sufficient dose to suppress the appetite and reduce the body mass.
Dietary restrictions in a young age may have a negative effect on the formation of muscles, bones and main systems of the body.
Thus, young people, taking Metermine 15mg need a balanced diet and a significant increase of physical activity.
Metermine 30 mg
Patients, who use Metermine 40mg, often complain of side effects.
The majority of overweight patients can deal with such mild side effects as dry mouth, sleep disorders, dizziness and nervousness.
Such Metermine side effects as an involuntary movement of the limbs, frequent or uncontrolled defecation may cause inconvenience and discomfort.
A significant increase in the blood pressure and heart rate can pose a real threat for health.
Metermine 30mg causes side effects rarely.
Patients, who have dangerous side effectscaused by Metermine 40mg weight loss pills, should reduce the dose down to Metermine 30mg.
If side effects do not disappear, better use Metermine 15mg.
During the anti-obesity therapy, Metermine 30mg weight loss pills can lessen the appetite and speed up the metabolism.
One of the main causes of obesity is a slowdown and violation of metabolism.
Therefore, the exclusion of this factor will cause a positive effect on the obesity treatment.
Metermine 30mg is the dosage, which is administered to overweight patients most often.
It happens because Metermine 30mg can effectively reduce the appetite without causing too many side effects.
Metermine 40 mg
Metermine 40mg is the highest dose an overweight or obese patient can take per day.
Metermine 40mg contains a larger amount of active substance Phentermine than other doses, and thus this dosage suppresses the appetite maximally.
In fact, Metermine 40mg not only can reduce the appetite maximally, but also can cause side effects and other negative reactions.
When using Metermine 40mg slimming pills, a patient has a high risk of:
- dyspnea and other breathing problems;
- difficulty of falling asleep and sleep problem;
- emotional instability or uncertainty;
- deterioration of spatial perception and stability.
The most severe side effects when using Metermine 40mg may cause a significant increase of the blood pressure and change in the heart rate.
That is why doctors recommend obese patients to take Metermine 40mg with caution.
To minimize the risk of side effects, follow a few simple recommendations:
- Take Metermine 40mg in the morning at one and the same time.
- Increase physical activity and keep a diet.
- Do not take more than one Metermine diet pill per day.
- Do not take Metermine in afternoon.
Recommended treatment duration with Metermine
Anyone willing to use these slimming pills, should remember that they must never use this medication for a long time.
So, when you begin using them, be ready that your appetite reduces greatly.
Don’t forget to reduce the amount of food in your daily menu, as well.
• The recommended time of use of Metermine is 5-6 weeks, maximum time of use – 12 weeks.
Maximal weight loss rate is observed on 3-4th week of using Metermine.
Within this period of time, an obese patient can lose a great amount of weight only if he keeps a diet and increases physical activity.
Proper use of these pills can help you reduce your body mass by approx. 15% within a short time and without painful hunger.
How to take Metermine capsules
Metermine weight loss capsules are designed for oral use.
Do not chew or break the capsule, regardless of the dosage.
It is recommended to take them in the morning with plenty of water.
Please note that you must not take more than one capsule per day, unless otherwise recommended by your physician.
Some patients misuse Metermine slimming pills in order to speed up their weight loss.
- increase the dose of Metermine on their own
- take more than one weight loss pills per day
- use Metermine for a time longer than prescribed by a doctor.
There were cases when patients had visited a couple of doctors to get more than one prescription for Metermine.
It is important to understand that you are using a powerful weight loss medication and it should be used in compiance with the doctor’s recommendations only.
Usually, a self-adjustment of the dose and treatment time with Metermine do not increase the weight loss rate.
A long-term Metermine abuse may cause many side effects, overdose, as well as physical and psychological dependence.
Metermine Side Effects
Some weight loss pills can cause severe side effects and therefore today they are not used for obesity treatment (e.g. Fenfluramine).
Metermine is not an exception and is capable of causing side effects, as well.
However, it is believed that the benefit from these diet pills is much greater than possible harm.
Side effects are associated with the action mechanism of Metermine.
Most side effects, caused by these slimming pills, occur in:
- The central nervous system (CNS)
- The cardiovascular system
- The gastrointestinal tract (GIT)
Generally, these slimming pills (Phentermine) are well tolerated in most patients.
Side effects manifestation depends on individual tolerability of a patient and Metermine dosage.
As already mentioned, side effects are most often caused by Metermine 40mg, rarely by 15mg.
In some people, Metermine 15 mg does not suppress the appetite to the maximum; hence, Metermine 30mg is considered an optimal dose for the majority of overweight or obese patients.
Usually, mild side effects do not require changing the dosage and disappear without special treatment within a short time (up to a week).
If severe side effects occur, doctors recommend reducing the dosage or discontinuing Metermine.
The active substance of these pills begins acting right in the brain parts, responsible for satiety.
Therefore, the common side effects manifest from the part of the CNS, for instance:
- Temporal loss of consciousness
- Erectile dysfunction or other sexual disorders
- Difficulty with falling asleep or insomnia
- Bad mood and aversion to activities
- Emotional instability or uncertainty
- Worry and anxiety.
Once again, to reduce the risk of these side effects, Metermine slimming pills must never be used in mental disorders.
Metermine drug interactions
Do not take Metermine within 14 days after the use of antidepressants of MAOIs group (e.g. Parnate, Tranylcypromine, Nardil and Phenelzine).
Besides, Metermine provides a significant impact on the blood pressure and changes the heart rhythm.
Many patients, suffering from obesity, have heart problems.
Therefore, they must be careful when taking Metermine slimming pills.
To minimize the risk of cardiovascular side effects, it is advised not to take drugs that affect the blood pressure and the heart work.
Metermine with medications for blood pressure
Patients should also inform the doctor if they are going to combine Metermine with medications to reduce the blood pressure, containing such active substances as:
- Clonidine (Catapres, Duraclon and Kapvay).
- Methyldopa (Aldomet, Aldoril and Aldoclor).
- Guanethidine (Esimil and Ismelin).
Even an overuse of coffee during Metermine therapy can affect the anti-obesity therapy and cause side effects.
During the therapy with these diet pills, the GIT side effects are usually rare.
The most common of them are: dryness in the mouth or unusual taste.
In addition, people may notice such unwanted side effects as uncontrolled defecation or constipation.
Metermine with alcohol
When using Metermine weight loss pills, you should refuse from alcohol consumption.
Alcoholic beverages can change the pharmacological effect of this weight loss medication and lead to unpredictable consequences.
Metermine safety and effectiveness
According to the results of clinical trials, scientists have proven that Metermine capsules help to lose weight even to those patients, who are severely obese.
The highest weight loss rate is reached during the first few weeks of treatment with this anorectic agent.
In 2-3 months after the initiation of the anti-obesity therapy, Metermine effectiveness decreases, so its use becomes pointless.
Long-term use of Metermine not only reduces the effectiveness of the obesity treatment, but also increases the risk of drug dependence.
Therefore, it is essential to comply with both the dosing regimen and the recommended treatment duration of no longer than three months in a row.
How to get a prescription for Metermine?
Metermine is a stimulant of the central nervous system (CNS), it requires a prescription from your treating physician or a bariatrician.
Metermine is available in local pharmacies and some online pharmacies.
A patient can get the prescription for Metermine after he was officially diagnosed obesity (BMI over 30).
Metermine prescription is also issued to those patients, whose overweight (BMI 27 to 30) is accompanied by hypertension, high level of lipids in the blood or type 2 diabetes.
Before buying Metermine, patients should visit a doctor and undergo a medical examination.
The purpose of medical examination is to determine whether a patient can use Metermine without harm to health.
Doctor can prescribe Metermine diet pills to those patients, who have no diseases, associated with the CNS, the work of heart and blood vessels.
After a medical examination and getting a prescription, you can buy Metermine weight loss pills at any pharmacy.
How to buy Metermine online
Being a popular Duromine generic, which is produced by the same manufacturer as the original drug, Metermine is also available for sale in local pharmacies, and also remains one of the most popular weight loss medications in such countries, as Australia, New Zealand and South Africa.
Even though, it is often out of stock, you can still wait. However, you can try to find an online source which sells Metermine or alternatives to this medication.
While doing our thorough search, we have found the largest Duromine community, where you can find a couple of sellers, who sell their unused or unwanted Duromine.
On this Duromine forum, we also found a seller, who has proven over time to be capable of providing the medications to people worldwide. You can check out positive feedbacks of the seller’s customers or choose the services of other proven sellers.
From the medical point of view, the main goal of anti-obesity drug therapy is not weight loss, but a reduction of cardiometabolic risks factors that always come along with this disease.
The choice of diet pills can affect both the weight loss rate and a patient’s health.
Metermine and similar generic drugs are the most popular weight loss pills in Australia, the USA, Canada and other countries of the world.
When using Metermine, most overweight patients have noted that their appetite almost disappeared.
This is why these pills are so popular.
Unlike other methods of obesity treatment, Metermine weight loss pills do not reduce weight by lessening the muscle mass or water in the body.
During the use of Metermine, the body mass reduction happens due to an increase of the fat burn rate.
Considering that Metermine diet pills are not meant for a long-term use, you should make an effort to achieve maximum results.
All the patients using Metermine slimming pills are recommended to keep a diet and change their lifestyle, so they usually do something for that.
However, to achieve a rapid weight loss, they are advised to visit a specialist in weight management.
Of course, you can come up with your own weight loss program, using the Internet and other mass-media information.
The most important thing in the use of Metermine slimming pills, is that you have a strong will power and are motivated enough to change your lifestyle.